Trabectedin (also known as YONDELIS) is an anti-tumor drug with significant efficacy against specific types of sarcomas. Its price, purchase methods, and interactions with other drugs are common concerns among patients. The original brand-name drug of Trabectedin exported to Turkey by Johnson & Johnson (USA) has a specification of 1mg, with a price of approximately 1,354 US dollars per box.

How Much Does Trabectedin Cost?

Trabectedin has not been launched in China and is not covered by China's medical insurance. Currently, there are no generic versions of Trabectedin available on the market, so patients need to purchase the overseas version of the drug.

Market Price

The price of Trabectedin varies depending on factors such as the manufacturer, specification, sales region, and purchase channel. Taking the original brand-name Trabectedin exported to Turkey by Johnson & Johnson (USA) as an example, the 1mg specification is priced at approximately 1,354 US dollars per box. This price is for reference only; the actual purchase price may fluctuate due to market changes, exchange rate variations, and other factors.

Factors Affecting the Price

The price of Trabectedin is influenced by multiple factors. Drug pricing policies, taxes, and logistics costs in different countries or regions will also affect the final selling price of Trabectedin. Additionally, the choice of purchase channel can impact the price—for instance, purchasing through formal medical institutions, pharmacies, or overseas drug purchase platforms may result in different prices.

How to Purchase Trabectedin?

Since Trabectedin has not been launched in China, it cannot be obtained from hospitals, pharmacies, or other channels within China.

Purchase Through Formal Channels

When purchasing Trabectedin, patients should give priority to formal medical institutions or pharmacies. The drugs provided by these channels are quality-assured, and they can also offer professional medication guidance and after-sales services. Patients can purchase Trabectedin through hospital pharmacies, chain pharmacies, or officially authorized online pharmacy platforms.

Overseas Drug Purchase

For patients who cannot purchase Trabectedin through formal channels in China, overseas drug purchase becomes an option. However, overseas drug purchase involves many risks. When choosing to buy drugs overseas, patients should carefully select the purchasing platform and verify the legality and safety of the drug source.

Trabectedin Drug Interactions

When using Trabectedin, patients should inform their doctors of all drugs they are currently taking, including prescription drugs, over-the-counter drugs, and health supplements. Doctors will adjust the medication plan based on the patient's specific situation.

Interaction with Cytochrome CYP3A Inhibitors

Trabectedin interacts with cytochrome CYP3A inhibitors. When Trabectedin is administered in combination with strong CYP3A inhibitors (such as ketoconazole, itraconazole, etc.), the systemic exposure of Trabectedin will increase, thereby raising the risk of adverse reactions. Patients taking Trabectedin should avoid concurrent use of strong CYP3A inhibitors.

Interaction with Cytochrome CYP3A Inducers

When Trabectedin is used in combination with strong CYP3A inducers (such as rifampicin, phenobarbital, etc.), the systemic exposure of Trabectedin will decrease, which may lead to reduced efficacy. Patients taking Trabectedin should also avoid using strong CYP3A inducers.

Through the information provided in this article, it is hoped that readers can gain a clear understanding of the price of Trabectedin, learn about formal purchase channels and related precautions, and grasp the knowledge of Trabectedin's interactions with other drugs, so as to make informed decisions regarding medication.