Losartan Potassium and Hydrochlorothiazide Tablets (Hyzaar) is a compound antihypertensive drug composed of losartan potassium (an angiotensin II receptor blocker, ARB) and hydrochlorothiazide (a diuretic).

Indications of Losartan Potassium and Hydrochlorothiazide Tablets (Hyzaar)

Hypertension Treatment

It is suitable for patients who require combined medication to control blood pressure. By lowering blood pressure, it reduces the risk of fatal and non-fatal cardiovascular events (such as stroke and myocardial infarction).

Note: This compound preparation is not recommended as initial treatment for hypertension, unless the patient has severely elevated blood pressure that requires rapid control.

Reduction of stroke risk in hypertensive patients with left ventricular hypertrophy.

Specifications and Properties of Losartan Potassium and Hydrochlorothiazide Tablets (Hyzaar)

HYZAAR 50/12.5

Composition: Each tablet contains 50mg losartan potassium + 12.5mg hydrochlorothiazide.

Properties: Yellow, oval, film-coated tablets, with the marking "717" printed on one side.

HYZAAR 100/12.5

Composition: Each tablet contains 100mg losartan potassium + 12.5mg hydrochlorothiazide.

Properties: White, oval, film-coated tablets, with the marking "745" printed on one side.

HYZAAR 100/25

Composition: Each tablet contains 100mg losartan potassium + 25mg hydrochlorothiazide.

Properties: Light yellow, oval, film-coated tablets, with the marking "747" printed on one side.

Excipient Description

All specifications contain inactive ingredients such as microcrystalline cellulose, lactose, and starch; some contain colorants (e.g., D&C Yellow No. 10 Aluminum Lake).

Storage Methods for Losartan Potassium and Hydrochlorothiazide Tablets (Hyzaar)

Temperature and Humidity

It is recommended to store at 20°C–25°C, and avoid exposure to high temperatures (e.g., above 30°C) or humid environments.

Packaging Protection

Keep the original packaging to prevent direct light exposure (some tablets are light-sensitive).

Child Safety

Store out of the reach of children to prevent accidental ingestion.

Expired Medication Disposal

Expired medications must be disposed of through professional medical waste channels and must not be discarded randomly.