Infigratinib is a targeted therapy drug for cholangiocarcinoma that acts against specific gene mutations (e.g., FGFR2 fusion). Due to its specificity and strict medication requirements, patients must exercise extra caution during the purchase process.
How to Purchase Infigratinib
Overseas Purchase
Patients may choose to consult and purchase Infigratinib at hospital pharmacies or authorized pharmacies in countries or regions where the drug has been launched.
Since drug prices may be affected by factors such as regional differences and exchange rate fluctuations, patients need to make a budget and plan in advance before purchasing.
Purchase via Medical Service Institutions
Patients can consult domestic overseas medical service institutions that cooperate with international pharmacies or pharmaceutical companies.
These institutions usually provide legal import channels and can offer professional consultation and guidance.
Precautions for Purchasing Infigratinib
Confirm the Necessity of Medication
Gene Testing: Infigratinib is only suitable for cholangiocarcinoma patients with FGFR2 fusion/rearrangement, and the mutation must be confirmed by an FDA-approved test.
Doctor Evaluation: Oncologists must evaluate the patient’s condition and medication plan to avoid purchasing the drug without professional guidance.
Verification of Drug Specifications and Packaging
Specifications: Infigratinib is available in 25mg and 100mg capsules, packaged in blister packs for a 21-day treatment course (e.g., a 125mg daily dose pack contains 21×100mg capsules + 21×25mg capsules).
Packaging Labeling: Authentic outer boxes should indicate the manufacturer (QED Therapeutics), batch number, expiration date, and FDA approval information. Capsules are imprinted with "INFI 25mg" or "INFI 100mg".
Transportation and Storage Conditions
Temperature Requirement: Store at 20°C~25°C; avoid exposure to high temperatures or freezing during transportation.
Light and Moisture Protection: Capsules should be sealed and stored in the original packaging to prevent moisture or light exposure.
Avoid Drug Interactions
Gastric Acid Modifiers: Avoid concurrent use with proton pump inhibitors (e.g., omeprazole). For H2 receptor antagonists or antacids, an interval of more than 2 hours between administrations is required.
CYP3A Inhibitors/Inducers: Drugs such as itraconazole and rifampicin may affect the efficacy of Infigratinib. Patients must inform doctors of all medications they are taking.
How to Identify Authentic vs. Counterfeit Infigratinib
Inspect Capsule Appearance
Color and Labeling: 25mg capsules come in bottles with white bodies and gray caps; 100mg capsules in bottles with white bodies and light orange caps. Both have black dosage text printed on them.
Texture: Capsules should be intact (no damage), with uniform powder inside (no clumping or unusual odor).
Verify Purchase Channel
Request Certificates: Ask the seller to provide invoices, imported drug registration certificates (if applicable), and cold chain transportation records.
Official Verification: Confirm the drug batch number through the pharmaceutical company’s customer service or the FDA official website.
