Cerdelga (Elglustat) is a prescription medication used for the treatment of adult patients with Type 1 Gaucher disease. Classified as a glucosylceramide synthase inhibitor, it has specific indications and strict medication requirements. Therefore, patients must pay special attention to the legitimacy of purchase channels and the identification of genuine vs. counterfeit drugs when buying it.

How to Purchase Cerdelga (Elglustat)

Overseas Purchase

Patients may choose to consult and purchase Cerdelga at hospital pharmacies or licensed retail pharmacies in countries or regions where the drug has been approved for marketing.

Since drug prices may be affected by factors such as regional differences and exchange rate fluctuations, patients need to make a budget and plan in advance before purchasing.

Purchase through Medical Service Institutions

Patients can consult domestic overseas medical service institutions that cooperate with international pharmacies or pharmaceutical companies.

These institutions usually provide legal import channels and offer professional consultation and guidance.

Precautions for Purchasing Cerdelga (Elglustat)

Strictly Follow Doctor’s Instructions

Genetic Testing Requirement: Before starting treatment, patients must undergo FDA-approved CYP2D6 genetic testing to determine their metabolic type (e.g., Extensive Metabolizers [EMs], Intermediate Metabolizers [IMs], or Poor Metabolizers [PMs]). Ultrarapid Metabolizers (URMs) are contraindicated for use.

Dose Adjustment: The dosage should be adjusted based on the patient’s metabolic type and liver/kidney function. Concomitant use with CYP2D6/CYP3A inhibitors (such as ketoconazole and fluconazole) should be avoided.

Inspect Drug Packaging and Labeling

Approval Information: The packaging should clearly state "Initial U.S. Approval: 2014" and the latest revision date.

Specification Labeling: Each capsule contains 84 mg of eliglustat. The capsules have a blue-green cap and a white body, with the black imprint "GZ02" on them.

Avoid Contraindicated Conditions

Patients with Hepatic Impairment: Use is contraindicated in patients with moderate to severe hepatic impairment, or mild hepatic impairment combined with the use of CYP2D6 inhibitors.

Patients with Cardiac Diseases: Use should be avoided in patients with prolonged QT interval, arrhythmias, or those taking Class IA/III antiarrhythmic drugs.

How to Identify Genuine vs. Counterfeit Cerdelga (Elglustat)

Check Details of Outer Packaging

Anti-Counterfeiting Markings: The packaging of genuine drugs should clearly display the batch number, expiration date, and manufacturer information (e.g., Genzyme Corporation).

Completeness of Instructions: The accompanying Prescribing Information must include comprehensive content on indications, usage, and warnings.

Verify Drug Characteristics

Capsule Appearance: Genuine capsules have a pearlescent blue-green cap and a pearlescent white body, with no damage or abnormal coloration.

Contents: The capsule contains a white to off-white powder. If caking, discoloration, or an unusual odor is found, the drug may be counterfeit.