Almogran (Almotriptan) is a selective serotonin receptor agonist belonging to the triptan class of drugs, specifically indicated for the acute treatment of migraine attacks.
Indications for Almogran (Almotriptan)
Treatment of Migraine in Adults
Almogran is indicated for adult patients with a history of migraine with or without aura, for the acute relief of migraine attacks.
It works by activating 5-HT1B/1D receptors, which causes constriction of intracranial blood vessels and inhibits the release of neuropeptides in the trigeminal nervous system, thereby blocking the pain transmission pathway of migraines.
Treatment of Migraine in Adolescents
This medication can be used for the acute treatment of migraine headache pain in adolescents aged 12 to 17 years, but the following conditions must be met: the patient has a history of migraine with or without aura, and untreated migraine attacks usually last 4 hours or longer.
It is particularly important to note that: the drug can only be used after a clear diagnosis of migraine is confirmed.
Its efficacy in relieving migraine-related symptoms in adolescents (such as nausea, photophobia, and phonophobia) has not been proven.
It is not indicated for migraine prophylaxis or the treatment of cluster headaches.
Important Limitations
It must not be used for the treatment of hemiplegic or basilar migraines.
If there is no response after the first dose administration, the migraine diagnosis needs to be re-evaluated.
Specifications and Properties of Almogran (Almotriptan)
Dosage Form and Strength
6.25 mg tablets: White, film-coated, round, biconvex tablets with a red imprint "2080".
12.5 mg tablets: White, film-coated, round, biconvex tablets with a blue stylized imprint "A".
The active ingredient of the tablets is almotriptan malate, whose chemical structure contains dimethylaminoethyl and pyrrolidine sulfonyl groups, with a molecular weight of 469.56.
Composition
In addition to the active ingredient, the tablet excipients include carnauba wax, cellulose, mannitol, polyethylene glycol, etc. The 6.25 mg tablets contain iron oxide, and the 12.5 mg tablets contain FD&C Blue No. 2 colorant.
Storage Methods for Almogran (Almotriptan)
Storage Conditions
Store at room temperature of 25°C (77°F); short-term storage within the range of 15-30°C (59-86°F) is permitted.
Safe Handling Recommendations
The medication should be stored out of the reach of children.
Expired or no longer needed medication should be properly disposed of to avoid environmental contamination.
