How should I use Cyramza(Ramucirumab)?

Dosage and Administration

CYRAMZA is administered intravenously, with dosing regimens varying by cancer type and combination therapy. For gastric cancer and hepatocellular carcinoma, the recommended dose is 8 mg/kg every two weeks. In non-small cell lung cancer, 10 mg/kg is given every two weeks with erlotinib, or on day 1 of a 21-day cycle with docetaxel. For metastatic colorectal cancer, 8 mg/kg is administered every two weeks prior to FOLFIRI. Infusions are typically over 60 minutes, reduced to 30 minutes if tolerated. Premedication with a histamine-1 receptor antagonist is required before each infusion.