How should I use Vyloy(zolbetuximab)?

Zolbetuximab is a monoclonal antibody targeting Claudin 18.2 (CLDN18.2), mainly indicated for the treatment of advanced gastric cancer. The specific dosage of this drug must be determined under the guidance of a doctor, and arbitrary dosage adjustments should be avoided.

Administration Method and Dosage of Zolbetuximab

What is the recommended dosage of zolbetuximab for adult patients?

The recommended first dose for adult patients is 800 mg/m². The dose can be reduced to 600 mg/m² from the second administration onwards, and further reduced to 400 mg/m² after an interval of 3 weeks.

What is the specific administration rate of zolbetuximab?

For patients who tolerate zolbetuximab well, the administration rate can be gradually increased 30-60 minutes after the start of administration. However, the specific rate must follow the guidance of a professional doctor.

What is the administration frequency of zolbetuximab?

The administration frequency is intravenous infusion for more than 2 hours every 2 weeks.