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Binimetinib(Mektovi)

Names
Mektovi,Binimetinib,比美替尼,贝美替尼
Indicatons
Adults with advanced or metastatic melanoma with BRAF V600E or V600K mutation.
Price:
Manufacturer:
‌Pierre Fabre
Dosage form:
TABLET
Validity period:
24 months

Reminder: The outer packaging is for reference only, please purchase and use under the guidance of a pharmacist. For read by medical and pharmaceutical professionals only.

Mektovi(Binimetinib) Instructions:Uses,Dosage, Side Effects

Binimetinib Tablets (15 mg) are a targeted therapy designed for the treatment of advanced or metastatic melanoma with a BRAF V600E or V600K mutation, often in combination with BRAF inhibitors like dabrafenib. Binimetinib works by inhibiting MEK1/2, key components in the MAPK signaling pathway, which is crucial for tumor cell proliferation and survival. The drug is also indicated for the treatment of non-small cell lung cancer (NSCLC) with the same mutation.

Administered orally, Binimetinib is typically prescribed in doses of 45 mg twice daily for adults, and treatment should be closely monitored for side effects, particularly hepatic toxicity and gastrointestinal issues. Regular monitoring of liver function is recommended during therapy.

Generic name
Binimetinib(Mektovi)
English name
Binimetinib
Alternative Names
Mektovi,Binimetinib,比美替尼,贝美替尼
Drug prices
Indications

Typically used in combination with encorafenib for the treatment of unresectable or metastatic melanoma with a BRAF V600E or V600K mutation.

Therapeutic Target
Mitogen-activated extracellular signal-regulated kinase 1 and 2 (MEK1/2) within the MAPK/ERK signaling pathway
Active Ingredients
Binimetinib
Dosage Form
TABLET
Specifications
15mg*45tablets/box
Dosage and Administration

Based on Mektovi, commonly administered as 45 mg orally twice daily in combination therapy.

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