Lynparza is indicated for multiple cancer types with specific genetic biomarkers.
It is used as maintenance therapy for advanced ovarian cancer with BRCA mutations or HRD-positive status, adjuvant treatment for high-risk early HER2-negative breast cancer with germline BRCA mutations, and treatment for metastatic breast, pancreatic, and prostate cancers with relevant genetic alterations. Patient selection must be confirmed through FDA-approved companion diagnostics.

