Sparsentan(Filspari) is clinically indicated for adult patients with primary immunoglobulin A nephropathy (IgAN) to reduce their proteinuria levels. Many patients and their families are more concerned about the efficacy of Sparsentan(Filspari) when they buy it, which is explained in more detail below.

What are the therapeutic effects of Sparsentan(Filspari)?

Sparsentan has demonstrated significant therapeutic efficacy in the PROTECT study. This international randomized, double-blind controlled study compared Sparsentan with irbesartan in patients with IgA nephropathy and proteinuria. The results of the study showed that after 36 weeks of treatment, the urine protein-to-creatinine ratio decreased by 49.8% compared with baseline in the Sparsentan group, which was significantly higher than the 15.1% in the irbesartan group. This significant reduction means that Sparsentan is excellent at reducing proteinuria, with a relative reduction of up to 41%.

Patients need to pay attention to the use of drugs should be carefully followed by the doctor's instructions, according to the doctor's treatment recommendations, and any adverse reactions in the process of medication should be contacted by the doctor in time for timely medication adjustment.

How should patients with primary immunoglobulin A nephropathy be monitored for progression?

Here's a closer look at how patients with primary immune globulin A nephropathy should be monitored for progression:

Observe your urine

Patients should always pay attention to changes in their urine output and urine color, which are important indicators of renal function. Accurate recording of 24-hour urine inflow and output will help detect abnormal fluctuations in kidney function in a timely manner. If a patient notices a persistent decrease in urine output, or a significant change in urine color, a high level of suspicion should be imposed, which may be a sign of a problem with kidney function.

Other symptoms

If symptoms such as headache, nausea, and vomiting occur, they should not be taken lightly, which may be a precursor to acute renal insufficiency.

Medical examination

In order to protect their health, patients should undergo regular professional medical examinations in addition to self-monitoring to assess their condition more accurately. With these meticulous monitoring measures, patients and the care team can identify and address potential kidney function problems in a timely manner. This proactive approach to monitoring is essential to stabilize the condition and prevent complications.

When purchasing medicines, it is important to ensure that the purchase channel is regular. It is recommended to choose a reputable and regular pharmacy or medical institution to purchase to ensure the quality of the medicine. Avoid buying medicines from unknown sources to avoid encountering counterfeit and shoddy products that can harm your health. Choose formal channels carefully.