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What is the efficacy and effect of Caprelsa?
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Article source: Seagull Pharmacy
Jun 23, 2025

Vandetanib(Caprelsa) is a targeted drug used to treat unresectable locally advanced or metastatic medullary thyroid lesions. It helps patients prolong survival and improve quality of life by inhibiting a variety of tyrosine kinases, blocking the growth and spread of diseased cells.

What is the efficacy and effect of Caprelsa?

Vandetanib blocks the growth and spread of diseased cells by inhibiting a variety of tyrosine kinases, making it particularly suitable for patients with unresectable locally advanced or metastatic medullary thyroid disease. It has demonstrated significant efficacy in clinical trials, helping patients prolong survival and improve quality of life.

Mechanism of action of Vandetanib

Vandetanib blocks the growth and spread of diseased cells by inhibiting tyrosine kinases such as EGFR, VEGFR, and RET. This multiple inhibitory effect makes it effective in the treatment of medullary thyroid lesions, helping patients to control disease progression.

Indications for Vandetanib

Vandetanib is indicated for patients with unresectable locally advanced or metastatic medullary thyroid disease. It helps patients prolong survival and improve quality of life by inhibiting the growth and spread of diseased cells. The recommended dose of Vandetanib is 300 mg orally once daily until disease progression or unacceptable toxicity.

The efficacy of Vandetanib is significant, but patients need to pay attention to their dietary principles when using it, and we will introduce the dietary principles of Vandetanib below.

Vandetanib dietary principles

The consumption of Vandetanib is not affected by food, patients can take it before or after meals, patients should pay attention to a balanced and healthy diet during the medication, and avoid intake of foods or drinks that may affect the absorption of the drug.

Eat a balanced diet

Patients should maintain a balanced diet with adequate intake of protein, vitamins and minerals while taking Vandetanib to enhance the body's immunity and resistance. Avoid foods high in fat and sugar to reduce the burden on the liver and kidneys.

Avoid foods that interfere with the absorption of the drug

Patients should avoid foods or beverages that may affect the absorption of the drug, such as grapefruit or grapefruit juice, while taking Vandetanib. These foods may interfere with the metabolism of the drug and affect its efficacy.

The dietary principles of Vandetanib require special attention from patients, and we will introduce the daily life considerations of Vandetanib.

Vandetanib Considerations for Daily Life

The use of Vandetanib requires special attention in the daily life of the patient, and the patient should regularly monitor blood pressure, cardiac and liver function during the drug to prevent possible serious adverse reactions.

Monitor blood pressure and heart function regularly

Vandetanib may cause elevated blood pressure and prolonged QT interval, and patients should have their blood pressure and cardiac function monitored regularly while taking the drug. If you experience symptoms such as dizziness and palpitations, you should seek medical attention in time, and your doctor may adjust the dose or stop taking the medication.

Monitor liver function regularly

Vandetanib may cause hepatotoxicity, and patients should have regular monitoring of liver function during use. The doctor will adjust the dose of the drug or stop the drug according to the patient's liver function indicators.

Vandetanib is a prescription drug, and patients should strictly follow the doctor's instructions when using it and have regular re-examinations to prevent possible serious adverse reactions.

Note: For internal discussion among medical personnel only. For specific medication, please consult the attending physician. Drug information may change over time. For the latest information, we recommend adding a medical consultant or consulting for free online.
Vandetanib(Caprelsa)
Vandetanib(Caprelsa)
Symptomatic or progressive medullary thyroid carcinoma, unresectable locally...
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