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Instructions for Adagrasib(Krazati)
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Article source: Seagull Pharmacy
Jul 02, 2025

Adagrasib(Krazati) is an innovative anti-related disease drug. This article will introduce the Chinese instructions in detail and discuss the precautions for use in special populations.

Instructions for Adagrasib(Krazati)

Understanding the detailed information of Adagrasib is the prerequisite for the correct use of the drug.

Drug name and ingredients

Adagrasib(Krazati) is an oral tablet with Adagrasib as the main ingredient. The drug is designed for the treatment of patients with non-small cell lung-related diseases carrying KRAS G12C mutations.

Indications and dosage

Adagrasib is suitable for adult patients with non-small cell lung-related diseases who have been confirmed to carry KRAS G12C mutations. Usage and dosage should follow the doctor's instructions. It is generally recommended to take it at a fixed time every day. The dosage is determined based on the patient's weight, condition, liver and kidney function and other factors.

Precautions and adverse reactions

During the use of Adagrasib, patients should regularly undergo blood routine tests and liver and kidney function tests. Common adverse reactions include nausea, vomiting, diarrhea, rash, etc. If severe, seek medical attention in time. Pregnant women, breastfeeding women and those with severe liver and kidney dysfunction should use with caution.

Special population use of adagrasib

Special populations should pay special attention to medication safety and dosage adjustment when using adagrasib.

Pregnant and breastfeeding women

Pregnant women using adagrasib may have adverse effects on the fetus, and breastfeeding women using the drug may pass it to the baby through breast milk. Therefore, pregnant and breastfeeding women should avoid using it, or use it with caution after weighing the pros and cons under the guidance of a doctor.

Elderly and children

When elderly people use adagrasib, they should adjust the dose according to their liver and kidney function and physical condition to avoid adverse reactions caused by drug accumulation. The safety and effectiveness of adagrasib for children have not yet been determined and should be avoided.

People with liver and kidney dysfunction

When people with liver and kidney dysfunction use adagrasib, they need to closely monitor liver and kidney function indicators and adjust the dose according to changes in indicators to avoid adverse reactions caused by abnormal drug metabolism.

Adagrasib is an innovative anti-related disease drug that provides a new treatment option for patients with non-small cell lung-related diseases carrying KRAS G12C mutations. However, the correct use of this drug, especially paying attention to the drug safety and dosage adjustment of special populations, is the key to ensuring the treatment effect and patient safety. Patients should fully understand the contents of the drug instructions, follow the doctor's instructions for medication, and regularly monitor their physical condition to detect and deal with adverse reactions in a timely manner.

Note: For internal discussion among medical personnel only. For specific medication, please consult the attending physician. Drug information may change over time. For the latest information, we recommend adding a medical consultant or consulting for free online.
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