Cobimetinib is a targeted therapy drug mainly used to treat unresectable or metastatic melanoma with BRAF V600E or K mutation. It inhibits the growth and spread of tumors by inhibiting the activity of BRAF protein kinase, blocking the growth and signal transduction of tumor cells. For patients who need to buy cobimetinib, it is very important to understand the purchase channels, contraindications and storage methods.

Where is cobimetinib generally sold?

Cobimetinib has not yet been launched in China, has not entered China's medical insurance, and there are no generic drugs on the market. Patients need to purchase it through regular medical service institutions.

Regular purchase channels

In order to ensure that genuine cobimetinib is purchased, patients should choose regular medical service institutions for purchase. These institutions usually have legal drug business qualifications and can provide reliable quality drugs. When purchasing, patients should carefully check the production date, expiration date and other information of the drug to avoid buying expired or substandard drugs.

Precautions for purchase

To ensure the reliability of the source of the drug and avoid buying fake or inferior drugs, read the drug instructions carefully, understand the indications, usage and dosage of the drug, and purchase and use it according to the advice of the doctor or pharmacist. Do not adjust the drug dosage or stop the drug on your own.

After understanding the purchase channels of cobimetinib, patients also need to pay attention to the contraindications of the drug.

Contraindications of cobimetinib

As a targeted therapy drug, cobimetinib has significant efficacy, but it also has certain contraindications. The following are some situations that need attention:

Absolute contraindications

Cobimetinib is prohibited for pregnant women. Because cobimetinib has embryo-fetal toxicity, pregnant women may cause harm to the fetus when taking it. Before using cobimetinib, pregnant women must undergo strict pregnancy tests and ensure that effective contraceptive measures are taken during the use of the drug.

Relative contraindications

Lactating women should not breastfeed during treatment with cobimetinib and within 2 weeks after the last dose; male and female patients with reproductive potential should take effective contraceptive measures while taking cobimetinib and within 2 weeks after taking cobimetinib; patients with abnormal heart function should use cobimetinib with caution because the drug may cause cardiomyopathy; patients with liver or kidney damage do not need to adjust the dose, but should closely monitor relevant indicators.

After understanding the contraindications of cobimetinib, patients also need to master the correct storage method.

Storage method of cobimetinib

The correct storage method is essential to ensure the quality and efficacy of cobimetinib.

Correct storage conditions

Avoid exposing the drug to high temperature, humidity or direct sunlight, and try to store cobimetinib at room temperature below 30℃ to avoid affecting the quality and efficacy of the drug.

Storage precautions

Make sure the drug is stored in a dry, light-proof place, keep the drug away from children to avoid accidental ingestion; you should also check the expiration date and production date of the drug regularly to avoid using expired drugs.

Warm reminder: Cobimetinib is an effective drug for the treatment of melanoma, but patients need to follow the doctor's instructions and the drug instructions when purchasing, using and storing the drug. If you have any questions or discomfort, you should consult a doctor or pharmacist in time.