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Adverse reactions of Cyclogest
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Article source: Seagull Pharmacy
Jul 15, 2025

Cyclogest (Progesterone suppositories) is a commonly used Progesterone drug that plays an important role in the treatment of various gynecological diseases such as menstrual disorders, luteal insufficiency, and threatened abortion. Like other drugs, Cyclogest also has certain adverse reactions and drug interactions. This article will discuss the adverse reactions of Cyclogest and its drug interactions in detail to help patients better understand and use the drug.

Adverse reactions of Cyclogest

The severity of adverse reactions of Cyclogest varies from person to person, and common ones include nausea, vomiting, dizziness, breast tenderness, etc. These reactions are mostly mild to moderate and usually resolve on their own within a few days after stopping the drug. However, some patients may also experience more serious adverse reactions, such as vaginal bleeding and weight gain.

For these reactions, patients should pay close attention to physical changes. If necessary, they should seek medical attention in time and inform the doctor of the drugs they are using.

Drug interactions of Cyclogest

Drug interactions refer to the interaction between two or more drugs when they are used at the same time, which may lead to enhanced or weakened drug efficacy or even new adverse reactions. For Cyclogest, its drug interactions are mainly manifested in the following aspects:

1. Interaction with other drugs

(1) Drugs that reduce the efficacy of Progesterone: If the patient is taking carbamazepine (such as for preventing cramps, treating certain types of pain or mood disorders), rifampicin (for treating infections) or phenytoin (such as for preventing cramps or treating certain types of pain), these drugs may reduce the efficacy of Progesterone.

Therefore, when using Cyclogest, be sure to tell your doctor or pharmacist about other drugs you are taking so that the doctor can adjust the treatment plan according to the specific situation.

(2) Vaginal products that are not recommended for simultaneous use: It is not recommended to use other vaginal products while using Cyclogest vaginally, because it is not known whether this will affect the treatment effect. If necessary, please consult a doctor or pharmacist.

2. Interaction with food

There is currently no clear evidence that there is an interaction between Cyclogest and food. In order to ensure effective absorption and utilization of the drug, it is recommended that patients maintain a light diet during medication and avoid spicy, greasy and other irritating foods.

Understanding and avoiding drug interactions of Cyclogest is crucial to ensure the safety and efficacy of the drug. Before using Cyclogest, patients must fully communicate with their doctors or pharmacists and follow their advice and instructions to ensure the effective use of the drug. Patients should pay close attention to changes in their bodies during the use of the drug. If they have any discomfort or questions, they should seek medical attention in a timely manner and inform their doctors of the drugs they are taking.

Note: For internal discussion among medical personnel only. For specific medication, please consult the attending physician. Drug information may change over time. For the latest information, we recommend adding a medical consultant or consulting for free online.
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