Anakinra is a drug used to treat interleukin-1 receptor antagonist deficiency (DIRA). As a synthetic interleukin-1 receptor antagonist, it can replace the IL-1RA lacking in the patient's body, thereby effectively reducing inflammatory responses and arthritis pain. This article mainly explains the purchase channels of Anakinra.

Purchase channels of Anakinra

Patients can purchase Anakinra drugs in the following ways:

1. Purchase at foreign hospital pharmacies

Patients can hold a doctor's prescription and purchase the required Anakinra at a regular hospital pharmacy. Hospital pharmacies usually have professional pharmacists to provide guidance and services, but they need to pay attention to domestic and international drug import and export regulations to ensure legality and safety.

2. Domestic regular medical companies

Many regular medical companies usually cooperate with foreign pharmacies or pharmaceutical companies to help patients purchase the required drugs. Patients can submit orders online or offline and pay the fees in the agreed manner. It is very important to choose a reliable purchasing channel to ensure that regular and safe drugs are obtained.

3. Participation in clinical trials or drug import exceptions

Clinical trials refer to the testing and research of drugs in the clinical stage. Patients can obtain drugs by participating in relevant clinical trials. Drug import exceptions refer to special circumstances in which patients can apply for drug import exceptions to obtain foreign drugs that have not yet been marketed in China. This method requires patients to work closely with doctors and relevant institutions to meet the corresponding conditions and requirements.

The current manufacturer of Anakinra is SOBI of Sweden, with a specification of 100mg*4 small boxes*7 (a total of 28 sticks), but the price is affected by many factors such as exchange rates and local laws and regulations, and is variable, so the price is for reference only.

Recommended dosage of Anakinra

Before using Anakinra, patients need to understand some important information about its usage and dosage to ensure correct use and obtain the best therapeutic effect.

1. Treatment of active rheumatoid arthritis

The recommended dose is 100mg/day, subcutaneous injection every day. Higher doses will not lead to higher reactions and should be administered at approximately the same time every day.

2. Treatment of cryoprotein-associated periodic syndrome (CAPS)

For patients with multisystem inflammatory disease (NOMID), the recommended starting dose of Anakinra is 1-2 mg/kg. To control active inflammation, the dose can be individually adjusted to a maximum of 8 mg/kg per day, and the dose is adjusted in increments of 0.5-1 mg/kg. It is generally recommended to dosing once a day, but it can also be divided into 2 doses per day. Each syringe is for single use only, and a new syringe must be used for each administration. The unused portion should be discarded after each administration.

3. Interleukin-1 receptor antagonist deficiency (DIRA)

For patients with interleukin-1 receptor antagonist (DIRA) deficiency, the recommended starting dose of Anakinra is 1-2 mg/kg. To control active inflammation, the dose can be individually adjusted to a maximum of 8 mg/kg per day, and the dose is adjusted in increments of 0.5-1 mg/kg.

Anakinra is a 100mg/0.67ml solution, stored in a refrigerator at 2°C-8°C. Do not freeze or shake, avoid light, and avoid using it again if the drug deteriorates.

Patients should follow the usage and dosage instructions on the Anakinra label, avoid adjusting the dosage of the drug or using other drugs on their own to avoid increasing the risk of adverse reactions. If injection site reactions, upper respiratory tract infections, headaches, vomiting and other discomfort occur, they need to consult a doctor in time.