Dacomitinib, with the English name Dacomitinib, is originally developed by Pfizer Inc. of the United States. It is a highly effective drug for the treatment of metastatic non-small cell lung cancer (NSCLC) with positive epidermal growth factor receptor (EGFR) mutations. Its price varies depending on different versions and specifications. This article will elaborate in detail on how to purchase Dacomitinib economically. So, how to buy Dacomitinib at a lower cost?

How to Buy Dacomitinib at a Lower Cost

For patients who need to take Dacomitinib for a long time, the key is to select a version with higher cost-effectiveness while ensuring the quality of the drug.

Understand the Prices of Different Versions

There are multiple versions of Dacomitinib. The Pfizer version is relatively expensive, costing approximately $858 per box (45mg*30 tablets), while the Everest (Bangladesh) version and the Lucius (Laos) version are relatively cheaper. The above prices are for reference only.

Compare Purchasing Channels

When purchasing Dacomitinib, you can make comparisons through formal overseas pharmacies, medical institutions, or online platforms. These channels usually provide detailed product information and price comparisons, which help patients make informed choices.

Pay Attention to Preferential Activities and Policies

Patients can also pay attention to preferential activities or policies launched by pharmaceutical companies, pharmacies, or medical institutions, such as discounts and "buy one get one free". These activities can often further reduce the cost of purchasing drugs and alleviate the economic burden on patients.

Adverse Reactions of Dacomitinib

Understanding the adverse reactions of Dacomitinib is quite important for patients to use the drug safely.

Common Adverse Reactions

The most common adverse reactions of Dacomitinib include diarrhea, rash, paronychia, stomatitis, etc., with a relatively high incidence rate. These reactions usually occur in the early stage of treatment and may gradually alleviate or disappear as the treatment continues.

Severe Adverse Reactions

Although rare, Dacomitinib may also cause severe adverse reactions, such as interstitial lung disease (ILD), severe diarrhea, and exfoliative skin reactions. These reactions may be life-threatening. Once relevant symptoms appear, patients should seek medical attention immediately and stop using the drug.

Handling Suggestions

For mild adverse reactions, patients can relieve them by adjusting the dosage, using moisturizers, or antidiarrheal drugs. However, for severe adverse reactions, patients must seek medical attention immediately and handle them in accordance with the doctor's guidance.

Precautions for the Use of Dacomitinib

To ensure the safe and effective use of Dacomitinib, patients need to follow the following precautions.

Dosage Adjustment

When using Dacomitinib, patients should adjust the dosage according to their personal conditions and the doctor's advice. For patients with adverse reactions or liver and kidney function impairment, it may be necessary to reduce the dosage or adjust the medication plan. Patients should take Dacomitinib at the same time every day and avoid missing doses or taking extra doses.

Avoid Drug Interactions

Dacomitinib may have interactions with other drugs, especially when used in combination with proton pump inhibitors (PPIs), which may significantly reduce its blood concentration. During the use of Dacomitinib, patients should avoid using PPIs at the same time and adjust the use of other drugs in accordance with the doctor's advice.

It is also recommended that patients pay close attention to their own conditions during the medication period, communicate with doctors in a timely manner, and adjust the treatment plan.