How well does Quviviq(Daridorexant) work?

Quviviq is a medication used for the treatment of insomnia. By acting on orexin receptors and antagonizing orexin neuropeptides, it has the effect of improving sleep quality and promoting sleep. The following is some basic information about the therapeutic effects of Quviviq. However, please note that individual differences exist, and specific conditions require consultation with a doctor or medical professional for further evaluation.

Therapeutic Effects of Quviviq

Trial Design

The efficacy of Quviviq was evaluated in two multicenter, randomized, double-blind, placebo-controlled, parallel-group studies. A total of 1,854 patients with diagnostic mental disorders and insomnia were randomly assigned to receive Quviviq or placebo once daily in the evening for three months.

Trial Results

The primary efficacy endpoints of the two trials were polysomnography (LPS, WASO) and self-reported total sleep time (sTST) from baseline to the 1st and 3rd months. Compared with the placebo group, the Quviviq group showed statistically significant improvements in both the 1st and 3rd months, with patients experiencing a substantial increase in sleep duration.