ORENCIA(Abatacept) Side Effects

Common side effects of ORENCIA include infections, headache, and respiratory symptoms, with serious adverse events like anemia, hypertension, and pneumonia observed in aGVHD patients.

Adverse Reactions and Side Effects of ORENCIA

In clinical trials, the most frequent adverse events in RA patients treated with ORENCIA include headache, upper respiratory tract infections, nasopharyngitis, and nausea. For patients receiving ORENCIA for aGVHD prophylaxis, common reactions include anemia, hypertension, CMV reactivation, pneumonia, pyrexia, and epistaxis. More severe reactions, such as acute kidney injury, hypermagnesemia, and decreased CD4 lymphocytes, have also been reported. As with all immunomodulatory treatments, hypersensitivity reactions and severe infections may occur. In pediatric patients, particularly those with JIA or PsA, gastrointestinal and respiratory side effects are notable.