How should I use this medicine?

ORENCIA dosage varies based on the patient’s condition, weight, and whether intravenous or subcutaneous administration is used.

Dosage and Administration of ORENCIA

For intravenous administration in RA and PsA, ORENCIA is given at 0, 2, and 4 weeks, then every 4 weeks thereafter. The dose is based on body weight: patients under 60 kg receive 500 mg, those between 60-100 kg get 750 mg, and those above 100 kg receive 1,000 mg. For subcutaneous use, adults should administer 125 mg weekly after an optional IV loading dose. Pediatric patients with pJIA or PsA are given 50-125 mg weekly based on their weight. In aGVHD prophylaxis, dosing varies by age and weight, with doses ranging from 10 mg/kg to 15 mg/kg.