How should I use Jaypirca(Pirtobrutinib)?

Guidelines on how to use the medication.

Recommended Dosage

The standard recommended dosage is 200 mg taken orally once daily, with or without food. Tablets must be swallowed whole with water; they must not be cut, crushed, or chewed. Dosage modifications are necessary for patients with severe renal impairment (eGFR 15-29 mL/min), requiring a reduction to 100 mg once daily. Management of adverse reactions may involve treatment interruption, dose reduction, or permanent discontinuation based on severity.