How should I use Ziihera(Zanidatamab)?

This section outlines the recommended dosing regimen and administration protocol.

Recommended Dosing Regimen

The prescribed dosage is 20 mg/kg administered by intravenous infusion every two weeks. Premedication with acetaminophen, an antihistamine, and a corticosteroid is mandatory 30-60 minutes before each infusion to mitigate reactions. Initial infusions are administered over 120-150 minutes, with potential reductions to 90 or 60 minutes for subsequent doses if well-tolerated. Dosage adjustments or discontinuation are required for specific adverse reactions.