


Reminder: The outer packaging is for reference only, please purchase and use under the guidance of a pharmacist. For read by medical and pharmaceutical professionals only.
This section summarizes the key characteristics of VESANOID.
VESANOID (tretinoin) is an orally administered retinoid capsule indicated for the treatment of a specific form of leukemia. Its active component, all-trans retinoic acid, functions by inducing cellular differentiation in malignant promyelocytes. It is specifically targeted for patients with confirmed genetic markers and requires careful clinical management due to its significant side effect profile and specific handling requirements.
VESANOID is indicated for the induction of remission in adults and pediatric patients 1 year of age and older with acute promyelocytic leukemia (APL) characterized by the presence of the t(15;17) translocation or PML/RARα gene expression, and who are refractory to or who have relapsed from anthracycline chemotherapy or for whom anthracycline-based chemotherapy is contraindicated.
The recommended dosage of VESANOID is 22.5 mg/m2 orally twice daily until complete remission is documented. Discontinue VESANOID 30 days after achievement of complete remission or after 90 days of treatment, whichever occurs first.
