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Daurismo(Glasdegib)
Reminder: The outer packaging is for reference only, please purchase and use under the guidance of a pharmacist. For read by medical and pharmaceutical professionals only.
Daurismo(Glasdegib) Instructions:Uses,Dosage, Side Effects
DAURISMO, with the generic name glasdegib, is an oral hedgehog pathway inhibitor. Its primary active component is glasdegib maleate. This targeted therapy is formulated as a film-coated tablet and is specifically designed for use in combination with low-dose cytarabine for a defined patient population with acute myeloid leukemia.
Used in combination with low-dose cytarabine for the treatment of newly diagnosed acute myeloid leukemia (AML) in adults who are ≥75 years old or have comorbidities that preclude intensive induction chemotherapy.
The recommended dosage is 100 mg orally once daily on days 1 to 28 of each 28-day cycle, in combination with subcutaneous cytarabine 20 mg twice daily on days 1 to 10. It should be taken with or without food. Tablets must not be split or crushed. Dose modifications may be required based on adverse reactions or drug interactions.
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