Tazemetostat, whose trade name is Tazemetostat, is a targeted drug used to treat epithelioid sarcoma and follicular lymphoma. Although it performs well in treating certain lesions, patients may experience some obvious side effects during use. Understanding these side effects and their responses will help patients better manage the treatment process.

What are the obvious side effects of Tazemetostat(TAZVERIK) on patients?

Tazemetostat may cause a series of side effects when treating epithelioid sarcoma and follicular lymphoma. These side effects vary by patient's specific situation, and common ones include fatigue, nausea, decreased appetite, vomiting, and constipation.

Common side effects in patients with epithelioid sarcoma

For patients with epithelioid sarcoma, the most common side effects of Tazemetostat include pain, fatigue, nausea, decreased appetite, vomiting, and constipation. These side effects may affect the patient’s quality of life, but can usually be alleviated with appropriate supportive treatment.

Common side effects in patients with follicular lymphoma

For patients with follicular lymphoma, the most common side effects of Tazemetostat include fatigue, upper respiratory tract infection, musculoskeletal pain, nausea, and abdominal pain. These side effects are usually more obvious in the early stages of treatment, and some patients may gradually adapt as the treatment progresses.

Although the side effects of Tazemetostat are common, patients can effectively deal with these discomforts through appropriate relief methods.

How to relieve side effects of Tazemetostat？

Although the side effects of Tazemetostat are common, patients can effectively deal with these discomforts through appropriate relief methods. Common relief methods include diet adjustment, medication and supportive treatment.

Relieve fatigue and nausea

Fatigue and nausea are common side effects of Tazemetostat. Patients can relieve nausea by adjusting their diet, choosing easy-to-digestible foods, and avoiding greasy and spicy foods. For fatigue, patients should ensure adequate rest and perform appropriate mild exercise, such as walking or yoga, to enhance their physical strength.

Relieve constipation and decreased appetite

Constipation and decreased appetite are another common side effect. Patients can relieve constipation by increasing their dietary fiber intake, drinking more water, and exercising appropriately. For decreased appetite, patients can try eating less and more meals and choose foods with high nutritional density, such as nuts, yogurt and eggs.

With appropriate remission methods, patients can effectively deal with the side effects of Tazemetostat.

What can I check during the medication process？

During the treatment of Tazemetostat, patients should undergo regular examinations, including liver function, blood routine and lesion markers.

Regularly monitor liver function

Tazemetostat may cause hepatotoxicity, and patients should monitor liver function regularly during medication. The doctor will adjust the dose of the drug or suspend the medication based on the patient's liver function indicators.

Regular blood tests

Routine blood tests can help doctors understand the patient's blood condition, especially the number of white blood cells, red blood cells and platelets. These indicators can reflect the patient's immune function and anemia, and help doctors adjust their treatment plans in a timely manner.

Tazemetostat is a prescription drug. Patients should strictly follow the doctor's instructions when using it, conduct regular reviews to prevent possible serious adverse reactions.