Selpercatinib(Retevmo/LOXO-292) is an effective treatment for RET fusion or mutation-positive lesions, and since it was approved by the US FDA in 2020, it has provided new treatment hope for many patients. This article will elaborate on how to buy Selpercatinib, the side effects when taking it, and the ways and means to alleviate the side effects.

How to buy Selpercatinib?

Selpercatinib is an innovative drug that needs to be purchased through formal and reliable channels.

Formal purchase channels

Selpercatinib has been marketed in China, and patients can purchase it through tertiary hospitals, regular pharmacies or qualified medical service institutions. The quality of the drugs provided by these channels is guaranteed, and they can provide professional medication guidance.

Cross-border e-commerce platform

In addition to traditional channels, patients can also purchase Selpercatinib through cross-border e-commerce platforms. However, it is necessary to pay attention to choosing a reputable platform, carefully check the drug information, and pay attention to the production date, expiration date and storage conditions of the drug when purchasing, so as to avoid buying expired or improperly stored drugs.

When purchasing Selpercatinib, patients should choose a formal and reliable channel to determine the quality and safety of the drug.

What are the side effects when taking Selpercatinib?

Although Selpercatinib is effective, a series of side effects may occur during taking.

Common adverse reactions

After taking Selpercatinib, patients may experience common adverse effects such as edema, diarrhea, fatigue, dry mouth, high blood pressure, abdominal pain, constipation, rash, nausea, and headache. Most of these reactions are mild to moderate and are tolerated by most patients.

Serious side effects

Some patients may have serious side effects, such as hepatotoxicity, interstitial lung disease/pneumonia, QT interval prolongation, and bleeding events. These side effects can be life-threatening, and it is important to seek medical attention and adjust treatment as directed.

Patients should pay close attention to their body reactions when taking Selpercatinib in total and seek medical attention immediately if serious side effects occur.

Ways and means to alleviate the side effects of Selpercatinib

For the possible side effects of Selpercatinib, patients can take a series of measures to alleviate them.

Adjust the dose of medication

For patients with mild adverse reactions, the dosage can be appropriately adjusted under the guidance of a doctor to reduce symptoms. However, do not increase or decrease the dose on your own, as this may affect the efficacy or aggravate the side effects.

Symptomatic treatment

Symptomatic treatment can be taken for different types of side effects. For example, patients with diarrhea can take antidiarrheal drugs; Patients with hypertension should adjust antihypertensive medications; Patients who develop a rash may be given anti-allergy medications, etc. At the same time, maintaining a good lifestyle and mindset can also help reduce side effects.

The key to alleviating the side effects of Selpercatinib is to detect and treat symptoms in a timely manner, while maintaining good lifestyle habits and mindset to improve quality of life.