Thyrogen (Thyrotropin α) is an important therapeutic drug. The side effects, precautions, dosage adjustments and aseptic operation of the drug are very important information for patients who need to use this drug. 

What are the side effects and precautions of Thyrogen (Thyrotropin α)?

When using Thyrogen, patients may experience some side effects, and there are also some important precautions that need to be followed, so as to better ensure the safety of patients' medication.

Common side effects

The most common adverse reactions (>5%) of Thyrogen are nausea and headache, which are generally mild and will gradually disappear after the end of treatment. However, if the symptoms persist or worsen and are not relieved, we still recommend that patients seek medical attention in time.

Precautions for using Thyrogen

When using Thyrogen, patients need to pay attention to the following points:

1. For patients with a large amount of thyroid tissue still in situ or functional thyroid lesion metastasis, Thyrogen may cause a brief but significant increase in serum thyroid hormone concentration, thereby inducing hyperthyroidism. Such patients should closely monitor thyroid function and receive treatment if necessary.

2. Patients without central nervous system metastases may experience a stroke within 72 hours of Thyrogen administration. Adequate hydration before using Thyrogen can reduce the risk of stroke.

3. After treatment with Thyrogen, residual thyroid tissue or distant metastases may suddenly, rapidly, and painfully enlarge. For such patients, pretreatment with glucocorticoids should be considered to relieve symptoms.

4. If Thyrogen is administered with radioactive iodine, patients also need to be aware of the risks associated with radioactive iodine therapy. Before taking the drug, patients should fully understand these risks and fully communicate with their doctors.

5. For special populations, such as pregnant women, breastfeeding women, children, the elderly, and patients with renal impairment, the use of Thyrogen requires special caution. These patients should take the drug under the guidance of a doctor and closely monitor the reaction after taking the drug.

After understanding the side effects and precautions of Thyrogen, we will next introduce how to adjust the dose when adverse reactions occur.

Adverse reactions and dose adjustment of Thyrogen (thyroid stimulating hormone for injection)

When using Thyrogen, if the patient has adverse reactions, the doctor may adjust the dose according to the patient's specific situation and the degree of reaction.

The dose adjustment of Thyrogen should follow the following principles:

1. Patients should not adjust the dose by themselves. The dose adjustment should be made according to the patient's specific situation and the doctor's advice. Self-adjustment may affect the efficacy or increase the risk of adverse reactions.

2. When adjusting the dose, the doctor should comprehensively consider the patient's age, weight, renal function and other factors.

Dose adjustment in special circumstances

If the patient has severe adverse reactions or renal impairment, the doctor may make further adjustments to the dose. For patients with renal impairment, since Thyrogen may be metabolized slowly, the doctor may appropriately reduce the dose to avoid drug accumulation in the body.

Warm reminder: During the use of Thyrogen, patients should communicate with the doctor regularly and provide timely feedback on medication and physical condition. At the same time, patients should follow the doctor's instructions for medication and monitoring. When using Thyrogen, please be sure to comply with aseptic operation specifications.