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Who is Rasburicase (Fasturtec) suitable for?
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Article source: Seagull Pharmacy
Jul 17, 2025

Rasburicase (Fasturtec) is a recombinant urate oxidase that has a significant therapeutic effect in the medical field.

Who is Rasburicase (Fasturtec) suitable for?

Rasburicase is mainly suitable for blood patients with high-risk cell lysis syndrome. When these cells are eliminated by chemotherapy drugs or other treatments, a large amount of purine metabolites will be released, of which uric acid is one of the main metabolites. Due to the limited solubility of uric acid in plasma, when the concentration of uric acid is too high, it will be deposited in the kidneys and other tissues, leading to serious consequences such as renal insufficiency.

Rasburicase can effectively reduce plasma uric acid levels and alleviate the symptoms of lysis syndrome. It further oxidizes uric acid into urea capsules and hydrogen peroxide, greatly increasing the solubility of uric acid, making it easier to be excreted by the kidneys. This not only helps to reduce the burden on the kidneys, reduce the risk of renal insufficiency and acute renal failure, but also helps to improve the quality of life of patients.

In addition to the applicable population, patients also need to understand how to store Rasburicase.

How to store Rasburicase (Fasturtec)

Rasburicase is an important drug, and its storage conditions are crucial for patients.

1. Temperature control

Rasburicase should be stored at 2-8℃. This is a refrigerated temperature that can effectively maintain the stability and activity of the drug. Please make sure to store the drug in the refrigerator, but do not freeze it, because too low a temperature may destroy the molecular structure of the drug.

2. Store away from light

Rasburicase should be stored away from light. Light may cause the drug to decompose or deteriorate, so make sure the drug packaging is intact and avoid direct sunlight. If the drug packaging has been opened, it should be used up as soon as possible or stored according to the doctor's instructions.

3. Humidity control

The humidity of the drug storage environment should be moderate. Excessive humidity may cause the drug to absorb moisture, agglomerate or mold, affecting the efficacy and safety of the drug. Please store Rasburicase in a dry, ventilated place and avoid contact with a humid environment.

4. Intact packaging

The packaging of Rasburicase should be intact. Any damage or leakage may cause the drug to be contaminated or deteriorate. If the packaging is found to be damaged or leaking, please stop using it immediately and contact your doctor or pharmacist.

5. Expired drugs

Please check the shelf life of Rasburicase. Expired drugs may have lost their efficacy or produced harmful substances, so do not use expired Rasburicase. Please follow the instructions on the drug packaging and use it within the shelf life.

6. Special storage conditions

In some special cases, such as extreme environments such as high temperature, high humidity or severe cold, additional storage measures may be required to protect Rasburicase. Please follow the instructions of your doctor or pharmacist to ensure that the drug maintains its stability and activity during storage.

Correct storage conditions are key to ensuring the efficacy of Rasburicase. Please be sure to follow the above storage recommendations to ensure that the drug works best during treatment. If patients have any questions or uncertainties about the storage of drugs, please consult your doctor or pharmacist for advice.

Note: For internal discussion among medical personnel only. For specific medication, please consult the attending physician. Drug information may change over time. For the latest information, we recommend adding a medical consultant or consulting for free online.
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