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Can Rasburicase (Fasturtec) be used for a long time?
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Article source: Seagull Pharmacy
Jul 17, 2025

Rasburicase (Fasturtec) is a drug used to treat and prevent malignant blood cells, especially in chemotherapy-induced hyperuricemia.

Can Rasburicase (Fasturtec) be used for a long time?

The question of whether Rasburicase can be used for a long time needs to be considered comprehensively from multiple angles.

From the perspective of the therapeutic principle of the drug, Rasburicase reduces the level of uric acid in the blood by catalyzing the oxidation of uric acid into metabolites that are more easily soluble and excreted. This mechanism is relatively effective in relieving the symptoms of hyperuricemia in the short term, but long-term use of Rasburicase may bring some potential problems. The use of Rasburicase may induce the body to produce antibodies. Such antibodies may bind to Rasburicase, reduce its efficacy, and even cause allergic reactions. Patients with a history of allergic reactions need to be particularly careful when using Rasburicase and closely monitor possible allergic reactions during use.

Long-term use of Rasburicase may have a certain impact on the patient's immune system. Although Rasburicase itself does not directly act on the immune system, it reduces the pressure of hyperuricemia on the immune system by lowering uric acid levels. If patients use Rasburicase for a long time, it may cause the body's ability to regulate uric acid levels to decrease, increasing the risk of recurrence of hyperuricemia in patients.

Rasburicase may also interact with other drugs. When using Rasburicase, patients need to inform their doctors of other drugs they are using in a timely manner so that doctors can assess the possible risk of drug interactions. In addition, whether patients use Rasburicase for a long time needs to be evaluated based on the specific situation of the patient. For example, factors such as the patient's age, health status, and treatment plan may affect the use of Rasburicase. For young patients in good health, they may be able to tolerate longer-term Rasburicase treatment. For elderly, frail, or other patients with complications, the risks of using Rasburicase need to be carefully assessed.

Rasburicase must be used under the guidance of a doctor. The doctor will develop a personalized treatment plan based on the patient's specific situation and tell the patient how to use and store Rasburicase correctly. Patients should strictly follow the doctor's instructions when using Rasburicase and must not change the dose or stop the medication without authorization.

Whether Rasburicase can be used for a long time needs to be evaluated based on the patient's specific situation. When using Rasburicase, patients should pay close attention to possible side effects and drug interaction risks, and receive personalized treatment under the guidance of a doctor.

Note: For internal discussion among medical personnel only. For specific medication, please consult the attending physician. Drug information may change over time. For the latest information, we recommend adding a medical consultant or consulting for free online.
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