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Goserelin treatment of breast cancer patients
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Article source: Seagull Pharmacy
Jul 23, 2025

Goserelin sustained-release injection is suitable for prostate cancer, uterine leiomyoma, and breast cancer. Goserelin can inhibit the secretion of pituitary gonadotropin, inhibit serum estradiol concentration, and prevent tumor development.

Goserelin treatment of breast cancer patients

Goserelin can inhibit the production of ovarian estrogen in premenopausal and perimenopausal women, reduce the plasma or serum estrogen levels of premenopausal or perimenopausal women, kill residual tumor cells, shrink tumors, and is suitable for the treatment of premenopausal and perimenopausal breast cancer, which can prolong the patient's survival time and improve the quality of life.

Side effects of Goserelin

The use of Goserelin may bring some side effects to patients:

1. Abnormal menstruation

Goserelin can reduce the estrogen level in women's bodies, leading to abnormal menstruation, such as reduced menstrual volume and prolonged menstrual cycle. Estrogen plays a vital role in the female physiological cycle. It affects the growth and shedding of the endometrium and determines whether menstruation is normal or not. When Goserelin reduces estrogen levels, it may cause abnormal phenomena such as decreased menstrual volume, prolonged menstrual cycle or irregular menstruation.

2. Abnormal ovarian function

Long-term use of Goserelin may have a certain impact on the patient's ovarian function, leading to decreased ovarian reserve function, premature ovarian failure, etc. The ovaries are responsible for producing eggs and secreting sex hormones. The use of Goserelin may interfere with the normal function of the ovaries, leading to decreased ovarian reserve function, and may even cause premature ovarian failure. Premature ovarian failure means that the ovaries lose their normal function prematurely, which may cause women to enter menopause early and have a series of related symptoms.

3. Weight gain and water and sodium retention

In addition to the above-mentioned reproductive system side effects, Goserelin may also cause weight gain and water and sodium retention. This is mainly because Goserelin may inhibit the secretion of certain hormones in the human body and affect the body's metabolism and water balance. Weight gain and water and sodium retention may cause discomfort to patients and may affect overall health.

These side effects do not occur in every user, and the severity and manifestations may also vary due to individual differences. Before using Goserelin, patients should describe their medical condition and medication history in detail to their doctor so that the doctor can assess the risk and develop a personalized treatment plan.

Note: For internal discussion among medical personnel only. For specific medication, please consult the attending physician. Drug information may change over time. For the latest information, we recommend adding a medical consultant or consulting for free online.
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