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ZOLADEX(Goserelin)

Names
戈舍瑞林,诺雷得,醋酸戈舍瑞林缓释植入剂
Indicatons
ZOLADEX is indicated for Locally Confined Prostate Cancer (Stage B2–C) or advanced prostate carcinoma.
Price:
Manufacturer:
TerSera Therapeutics
Dosage form:
IMPLANT
Validity period:

Reminder: The outer packaging is for reference only, please purchase and use under the guidance of a pharmacist. For read by medical and pharmaceutical professionals only.

ZOLADEX(Goserelin) Instructions:Uses,Dosage, Side Effects

Goserelin Acetate Implant (ZOLADEX®) is a sustained-release GnRH agonist used to suppress testosterone in prostate cancer. Administered subcutaneously every 12 weeks, it induces medical castration, slowing tumor progression. 

Key indications include locally advanced (Stage B2-C) and metastatic prostate cancer, often combined with radiation or flutamide. Risks include tumor flare, cardiovascular events, and injection site injury. Monitoring testosterone levels and managing hyperglycemia are critical during therapy.  

Generic name
ZOLADEX(Goserelin)
English name
Goserelin
Alternative Names
戈舍瑞林,诺雷得,醋酸戈舍瑞林缓释植入剂
Drug prices
Indications

Locally Confined Prostate Cancer (Stage B2–C): Used in combination with flutamide and radiotherapy. Initiated 8 weeks prior to radiation and continued during therapy.

Advanced Prostate Cancer: Palliative treatment for metastatic diseas.

Therapeutic Target
Gonadotropin-Releasing Hormone (GnRH) receptors in the pituitary gland. Suppresses luteinizing hormone (LH) and follicle-stimulating hormone (FSH), leading to testosterone reduction to castration levels.
Active Ingredients
Goserelin acetate
Dosage Form
IMPLANT
Specifications
3.6mg*1vial/box
Dosage and Administration

1. Dose: 10.8 mg administered subcutaneously every 12 weeks.

2. Site: Anterior abdominal wall below the navel line.

3. Technique:

3.1 Aseptic technique; avoid muscle/peritoneum penetration.

3.2 Insert needle at 30–45° angle; no aspiration required.

3.3 Monitor for vascular injury (risk in low BMI or anticoagulated patients).

4. Missed Dose: Adhere to 12-week schedule; brief delays permissible.

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