Dexamethasone is a synthetic long-acting glucocorticoid with potent anti-inflammatory and immunosuppressive effects. As a commonly used clinical corticosteroid, it plays an important role in the treatment of various diseases.

Indications of Dexamethasone

Primary Indications

Used in combination with other anti-myeloma drugs for the treatment of multiple myeloma (MM) in adults.

Through its potent anti-inflammatory and immunosuppressive effects, dexamethasone serves as a key combination component in the treatment regimens for multiple myeloma.

Usage Restrictions

Patients with hypersensitivity to dexamethasone or any of its components.

Patients with systemic fungal infections.

Dosage Form and Properties of Dexamethasone

Basic Dosage Form Characteristics

HEMADY® Dexamethasone Tablets are 20 mg white, round, biconvex tablets, with "20" imprinted on one side.

Chemical Composition

Corn Starch NF.

Lactose Monohydrate NF.

Magnesium Stearate NF.

Povidone NF.

Sodium Starch Glycolate NF.

Chemical Properties

The chemical name of dexamethasone is 9-fluoro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione. It has a molecular weight of 392.47 g/mol and a molecular formula of C₂₂H₂₉FO₅.

It is a white to almost white, odorless crystalline powder, stable in air, and almost insoluble in water.

Storage Methods for Dexamethasone

Storage of Unopened Drug

Store at 20°C to 25°C (68°F to 77°F).

Short-term fluctuations within the range of 15°C to 30°C (59°F to 86°F) are permitted.

Keep in a tightly closed, light-resistant container that is difficult for children to open.

Transportation Precautions

During transportation, the drug should be kept within the recommended temperature range, and exposure to extreme temperature and humidity conditions should be avoided.