Raloxifene (Evista) is a selective estrogen receptor modulator (SERM), primarily used for the treatment and prevention of osteoporosis in postmenopausal women, as well as reducing the incidence of invasive breast cancer in high-risk populations.

How to Purchase Raloxifene (Evista)

Overseas Purchase

Patients may choose to consult and purchase the medication at hospital pharmacies or legitimate drugstores in countries or regions where raloxifene has been launched.

Since drug prices may be affected by factors such as regional differences and exchange rate fluctuations, patients need to make a budget and plan in advance before purchasing.

Purchase through Medical Service Institutions

Patients can consult domestic overseas medical service institutions that cooperate with international pharmacies or pharmaceutical companies.

These institutions can usually provide legal import channels and offer professional consultation and guidance.

Precautions for Purchasing Raloxifene (Evista)

Strictly Follow Doctor's Instructions

The dosage is 60 mg taken orally daily; do not adjust the dosage on your own. If a dose is missed, there is no need to make up for it; continue with the original dosage on the next day.

It is necessary to supplement calcium (1500 mg/day) and vitamin D (400-800 IU/day) at the same time to enhance the therapeutic effect.

Contraindications and High-Risk Populations

Absolute Contraindications: History of venous thromboembolism (e.g., deep vein thrombosis, pulmonary embolism), pregnancy, or planned pregnancy.

Caution Required: Patients with hepatic insufficiency or high risk of stroke (e.g., atrial fibrillation, hypertension) need doctors to evaluate the risk-benefit ratio.

Be Alert to Drug Interactions

Avoid concurrent use with cholestyramine (a lipid-lowering drug), as it may reduce the absorption of raloxifene.

Patients using warfarin need to closely monitor the prothrombin time.

Monitoring of Adverse Reactions

Common side effects include hot flashes, leg cramps, peripheral edema, etc.

If symptoms such as dyspnea, chest pain, or visual abnormalities (which may indicate thrombosis or stroke) occur, seek medical attention immediately.

How to Distinguish Authentic Raloxifene (Evista) from Counterfeits

Packaging and Appearance

Features of Authentic Products: White oval film-coated tablets, with blue markings "4165" or "LILLY4165" on one side.

Integrity of Packaging: The original packaging should include anti-counterfeiting labels, batch numbers, and expiration dates, with no signs of damage or secondary packaging.

Instruction Manuals and Labels

Authentic products are accompanied by English instruction manuals, which contain detailed information such as ingredients, indications, and contraindications. Counterfeit products may have typographical errors or missing content.

Check the FDA approval number and manufacturer information (Otsuka Pharmaceutical Co., Ltd.).

Verification After Purchase

Before taking the medication for the first time, you can contact the pharmacy department of a hospital or a third-party testing institution to conduct component analysis.

Record any adverse reactions and promptly report them to the doctor or pharmacy. Abnormal reactions may indicate the risk of counterfeit drugs.