Sabril (vigabatrin) is a medication used for the treatment of refractory complex partial seizures and infantile spasms. Due to its specific safety risks, it is subject to strict regulation in many countries and regions around the world, including China.
How to Purchase Sabril (Vigabatrin)
Overseas Purchase
Patients may choose to consult and purchase Sabril at hospital pharmacies or authorized retail pharmacies in countries or regions where the medication has been launched.
Since drug prices may be affected by factors such as regional differences and exchange rate fluctuations, patients need to make a budget and plan in advance before purchasing.
Purchase via Medical Service Institutions
Patients may consult domestic overseas medical service institutions that cooperate with international pharmacies or pharmaceutical companies.
These institutions can usually provide legal import channels and offer professional consultation and guidance.
Precautions for Purchase and Use of Sabril (Vigabatrin)
Strictly Follow Medical Advice
The dosage of Sabril needs to be individually adjusted based on the patient’s age, body weight, and indication.
For adults treating complex partial seizures, the initial dosage is 1000 mg per day, with weekly increments thereafter.
For infantile spasms, the initial dosage is calculated based on body weight (e.g., 50 mg/kg per day).
Patients must not adjust the dosage on their own or discontinue the medication abruptly, as this may induce status epilepticus.
Professional Medical Monitoring
Since Sabril carries a risk of causing permanent vision loss, regular ophthalmological examinations are required during the medication period.
It is recommended to conduct an examination before treatment (no later than 4 weeks after starting the medication), and at least once every 3 months during treatment. Even 3–6 months after discontinuing the medication, follow-up examinations are still necessary.
Doctors need to evaluate the therapeutic benefits against potential risks. If no significant therapeutic effect is observed within 3 months (for complex partial seizures) or 2–4 weeks (for infantile spasms), consideration should be given to discontinuing the medication.
Risk Warnings and Contraindications
The package insert of Sabril clearly indicates that it may cause irreversible damage such as visual field defects and tunnel vision.
Caution is required when combining Sabril with other ophthalmic diseases or medications with ophthalmic toxicity.
Methods to Identify Authenticity of Sabril (Vigabatrin)
Verify Packaging Information
Authentic Sabril tablets are white film-coated oval tablets of 500 mg, with a score line on one side and "OV111" printed on the other side.
The oral solution powder is white to off-white granules, with each sachet containing 500 mg.
The packaging should be labeled with the drug batch number, expiration date, and manufacturer information (e.g., Lundbeck).
If the packaging is damaged, the printing is blurred, or the information is incomplete, high vigilance is required.
