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Vadadustat(Vafseo)

Names

伐度司他

Indicatons

Treatment of anemia in adults with chronic kidney disease (CKD) who have been on dialysis for at least three months.

Price:

Manufacturer:

Akebia Therapeutics

Dosage form:

TABLET

Validity period:

36 months

Reminder: The outer packaging is for reference only, please purchase and use under the guidance of a pharmacist. For read by medical and pharmaceutical professionals only.

Vafseo(Vadadustat) Instructions:Uses,Dosage, Side Effects

VAFSEO, with the generic name vadadustat, is an orally administered hypoxia-inducible factor prolyl hydroxylase (HIF-PH) inhibitor. It received initial U.S. approval in 2024. The medication is formulated as film-coated, immediate-release tablets designed for once-daily oral administration. Its primary pharmacological action involves stabilizing hypoxia-inducible factors to stimulate endogenous erythropoietin production, thereby supporting red blood cell formation in eligible patient populations.

Generic name

Vadadustat(Vafseo)

English name

Vadadustat

Alternative Names

伐度司他

Drug prices

Indications

VAFSEO is indicated specifically for the treatment of anemia due to chronic kidney disease in adult patients receiving dialysis for a minimum of three months.

Therapeutic Target

HIF Prolyl Hydroxylase (HIF-PH) Isoforms 1, 2, and 3.

Active Ingredients

Vadadustat (2-[[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino]acetic acid).

Dosage Form

TABLET

Specifications

300mg * 60 Tablets/Bottle

Dosage and Administration

The recommended starting dose is 300 mg taken orally once daily, with or without food.

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