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Vadadustat(Vafseo)

Names

伐度司他

Indicatons

Treatment of anemia in adults with chronic kidney disease (CKD) who have been on dialysis for at least three months.

Price:

Manufacturer:

Akebia Therapeutics

Dosage form:

TABLET

Validity period:

36 months

Reminder: The outer packaging is for reference only, please purchase and use under the guidance of a pharmacist. For read by medical and pharmaceutical professionals only.

Vafseo(Vadadustat) Instructions:Uses,Dosage, Side Effects

VAFSEO, with the generic name vadadustat, is an orally administered hypoxia-inducible factor prolyl hydroxylase (HIF-PH) inhibitor. It received initial U.S. approval in 2024. The medication is formulated as film-coated, immediate-release tablets designed for once-daily oral administration. Its primary pharmacological action involves stabilizing hypoxia-inducible factors to stimulate endogenous erythropoietin production, thereby supporting red blood cell formation in eligible patient populations.

Generic name

Vadadustat(Vafseo)

English name

Vadadustat

Alternative Names

伐度司他

Drug prices

Indications

VAFSEO is indicated specifically for the treatment of anemia due to chronic kidney disease in adult patients receiving dialysis for a minimum of three months.

Therapeutic Target

HIF Prolyl Hydroxylase (HIF-PH) Isoforms 1, 2, and 3.

Active Ingredients

Vadadustat (2-[[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino]acetic acid).

Dosage Form

TABLET

Specifications

300mg * 60 Tablets/Bottle

Dosage and Administration

The recommended starting dose is 300 mg taken orally once daily, with or without food.

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Side effects of Vadadustat

Vadadustat is used for anemia of chronic kidney disease in dialysis patients and may cause multiple types of adverse reactions involving the cardiovascular, hepatic, and gastrointestinal systems, requ...

Dietary precautions for patients with Vadadustat

Vadadustat is an oral treatment for anemia of chronic kidney disease, and diet and medication timing directly affect efficacy and safety, requiring special attention.1. Basic Relationship Between Medi...

Special population medication for Vadadustat

Vadadustat is used in adults with anemia of chronic kidney disease who have been on dialysis for at least 3 months, and use in special populations requires careful assessment of risks and benefits.1. ...

Storage environment for Vadadustat

The storage of vadadustat requires attention to temperature, packaging, and storage safety, and proper storage can ensure stable drug efficacy. The following is explained from three aspects: temperatu...

Precautions for the use of Vadadustat

Vadadustat is used for anemia in adults with chronic kidney disease who have been on dialysis for at least three months, and its use requires vigilance for risks such as thrombosis, liver injury, and ...

Side effects and adverse reactions of Vadadustat

Vadadustat is used for anemia in chronic kidney disease patients on dialysis, but it may cause serious adverse reactions such as thrombosis, liver injury, and increased blood pressure, requiring close...

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