Before taking this medicine

Key precautions include vitamin A supplementation, monitoring for ocular symptoms, and population-specific considerations.

Risk Mitigation and Monitoring

WAINUA reduces serum vitamin A levels; patients require daily vitamin A supplementation at recommended dietary levels. Excessive supplementation is contraindicated. Ophthalmologic referral is advised for symptoms like night blindness or dry eyes. 

Pregnancy and lactation require caution due to vitamin A's teratogenic potential, though fetal risk from WAINUA itself is undetermined. No dose adjustments are needed for elderly patients or mild organ impairment, but severe renal/hepatic dysfunction and pediatric use lack data.