Who can use Wainua(Eplontersen)?

Wainua (eplontersen) is indicated for adults with hereditary transthyretin-mediated amyloidosis (hATTR)-related polyneuropathy, as confirmed by healthcare providers.

Who can use Wainua(Eplontersen)?

Pregnant or breastfeeding women are not recommended due to unclear risks to fetal development and lack of data on milk excretion. Patients with severe renal/hepatic impairment are excluded from clinical studies, though mild-to-moderate impairment does not necessitate dose changes.

Key precautions include mandatory vitamin A supplementation to address serum level reductions and ophthalmological monitoring for deficiency symptoms. Always use under medical supervision, with contraindications currently unlisted but strict adherence to prescribing guidelines.