Before taking OGSIVEO(Nirogacestat)

Precautions for OGSIVEO include monitoring for diarrhea and potential ovarian toxicity in female patients.

Key Precautions:

Diarrhea: Severe cases of diarrhea may occur, necessitating close monitoring. If Grade 3 or 4 diarrhea is observed, dosage adjustments or treatment interruptions should be considered to avoid dehydration and electrolyte imbalances.

Ovarian Toxicity: Female patients, especially those of reproductive potential, should be informed about the potential risk of impaired ovarian function and fertility. Regular monitoring of ovarian function is recommended during treatment.

Other Precautions: Since no other specific contraindications are mentioned, monitoring for other adverse effects should be based on clinical judgment and patient response to treatment. Regular assessments are advised to identify and manage any emerging risks.