Factors Affecting the Price of Filspari

Filspari (sparsentan), used for immunoglobulin A nephropathy, has a price shaped by key factors. 

Factors Affecting the Price of Filspari

High R&D costs, from developing this dual endothelin-angiotensin receptor antagonist to clinical trials proving renal protection, drive pricing. Patent exclusivity lets Travere Therapeutics set premium rates without generic competition. 

Production complexities, including specialized manufacturing and quality control for its formulation, add costs. Market demand for rare kidney disease treatments and regional healthcare policies (e.g., insurance coverage) also influence patient out-of-pocket expenses, varying by region based on access and subsidy frameworks.