How well does Kineret(Anakinra) work?

Kineret (anakinra) is an interleukin-1 receptor antagonist indicated for the treatment of rheumatoid arthritis (RA), cryopyrin-associated periodic syndromes (CAPS), and deficiency of interleukin-1 receptor antagonist (DIRA), improving symptoms and controlling inflammation in these conditions.

How well does Kineret(Anakinra) work?

Kineret, a recombinant interleukin-1 (IL-1) receptor antagonist, is primarily used to treat moderately to severely active rheumatoid arthritis (RA), cryopyrin-associated periodic syndromes (CAPS), and deficiency of IL-1 receptor antagonist (DIRA). In RA, it reduces signs and symptoms, while slowing the progression of joint damage. For CAPS, particularly Neonatal-onset Multisystem Inflammatory Disease (NOMID), Kineret helps control active inflammation, with dosage tailored based on the patient’s condition. In DIRA, it replaces the deficient IL-1 receptor antagonist to control systemic inflammation. The drug’s effectiveness extends across these conditions, alleviating chronic inflammation and preventing disease flare-ups when used appropriately.