How well does Xcopri(Cenobamat) work?

Therapeutic Effects of XCOPRI in the Management of Partial-Onset Seizures

XCOPRI (cenobamate) is primarily indicated for managing partial-onset seizures in adult patients. As a novel antiepileptic drug, its therapeutic effects stem from its ability to reduce the frequency and severity of seizures. The drug acts on both sodium and GABA receptors, which are critical in neuronal excitability and inhibition, respectively. By modulating these channels, XCOPRI helps to stabilize neuronal firing and prevent seizure activity. Clinical trials have shown that titrating the dosage from 12.5 mg to a maximum of 400 mg daily can significantly reduce seizure frequency. As with other antiepileptic treatments, its use should be accompanied by close monitoring for any adverse effects or interactions. Not specified in the description: The exact mechanism by which cenobamate exerts its therapeutic effects at the molecular level is not fully elucidated.