How well does Pentetate calcium trisodium injection(Ditripentat-Heyl Amp.) work?

This part summarizes the clinical efficacy of Ca-DTPA in enhancing the elimination of radioactive contaminants.

Clinical Efficacy

Clinical data from a U.S. Registry demonstrates that Ca-DTPA significantly increases the urinary excretion of transuranium elements. Following a single 1-gram dose, the mean excretion enhancement factor was 25.7, indicating a substantial increase in radioactive elimination. The drug is most effective when administered promptly after contamination, as its chelating capacity is highest when radionuclides are still circulating and before they become sequestered in tissues like liver and bone.