Flopropione Tablets (Cospanon) is a medicine used to relieve spasms of the biliary tract, pancreas and urinary system. Clinically, it is commonly prescribed for biliary dyskinesia, cholelithiasis, cholecystitis, pancreatitis, urinary calculi and other related diseases.

Dosage and Administration, Recommended Dose of Flopropione Tablets (Cospanon)

Usual Adult Dose

(1) 40 mg tablets: For adults, the usual oral dose is 1 to 2 tablets (equivalent to 40 to 80 mg of Flopropione) three times a day, to be taken after each meal. For the treatment of urinary calculi in urology, the recommended dose is usually 2 tablets three times a day after meals.

(2) 80 mg tablets: For adults, the usual oral dose is 1 tablet (equivalent to 80 mg of Flopropione) three times a day, to be taken after each meal. It should be noted that except for urinary calculi, the regular dosage for other indications remains 40 to 80 mg three times a day.

(3) 40 mg capsules: For adults, the usual oral dose is 1 to 2 capsules (equivalent to 40 to 80 mg of Flopropione) three times a day, which may be administered regardless of meal times.

Principles for Dosage Adjustment

(1) The dosage should be appropriately adjusted according to the patient's age, severity of symptoms and therapeutic response.

(2) Individualized medication under the guidance of a physician is recommended, especially during the initial treatment period or when symptoms change.

Medication in Special Populations for Flopropione Tablets (Cospanon)

Geriatric Patients

(1) Geriatric patients are often accompanied by impaired physiological functions, with potentially slowed drug metabolism, making them more susceptible to adverse reactions.

(2) It is recommended to initiate treatment with a low dose; gradual dosage adjustment may be made under the physician's monitoring when necessary, and close observation should be conducted for the occurrence of gastrointestinal or allergic reactions.

Pregnant Women and Women Planning Pregnancy

(1) Sufficient human safety data on the use of this medicine during pregnancy are currently lacking. Administration is only considered when the definite therapeutic benefits outweigh the potential risks.

(2) The medication must be strictly taken under the guidance of a physician during the treatment period, with regular pregnancy monitoring implemented.

Lactating Women

(1) Whether this medicine is excreted in breast milk remains unclear.

(2) A comprehensive assessment of the necessity of treatment and the benefits of breastfeeding should be conducted before use. The decision to continue breastfeeding or suspend the medication shall be made jointly by the physician and the patient.

Patients with a History of Allergy

This medicine is contraindicated in patients with a previous allergic reaction to flopropione or any excipients (e.g., colorants, gels) contained in the preparation.