Sitagliptin/Metformin Hydrochloride Extended-Release Tablets (Janumet XR) is an innovative oral combination anti-diabetic formulation that integrates the dual advantages of a dipeptidyl peptidase-4 (DPP-4) inhibitor and a biguanide agent.
Indications for Sitagliptin/Metformin Hydrochloride Extended-Release Tablets (Janumet XR)
Primary Indication
Adjunctive treatment for type 2 diabetes in adults: Serving as an effective supplement to dietary control and exercise therapy, it is specifically indicated to improve blood glucose control in adult patients with type 2 diabetes.
Special Precautions
Contraindicated Populations: It must not be used for the treatment of patients with type 1 diabetes.
Risk of Pancreatitis: No systematic studies have been conducted in patients with a history of pancreatitis, so it cannot be determined whether the use of this drug in such patients will increase the risk of developing pancreatitis. A rigorous assessment of medication safety is necessary.
Dosage Strengths and Physical Characteristics of Sitagliptin/Metformin Hydrochloride Extended-Release Tablets (Janumet XR)
Sitagliptin 100 mg / Metformin Hydrochloride 1000 mg Extended-Release Tablets
Physical Appearance: Blue, biconvex, oval-shaped film-coated tablets.
Identification Marking: Imprinted with the code "81" on one side as an anti-counterfeiting mark.
Sitagliptin 50 mg / Metformin Hydrochloride 500 mg Extended-Release Tablets
Physical Appearance: Light blue, biconvex, oval-shaped film-coated tablets.
Identification Marking: Imprinted with the code "78" on one side.
Sitagliptin 50 mg / Metformin Hydrochloride 1000 mg Extended-Release Tablets
Physical Appearance: Light green, biconvex, oval-shaped film-coated tablets.
Identification Marking: Imprinted with the code "80" on one side.
Storage Instructions for Sitagliptin/Metformin Hydrochloride Extended-Release Tablets (Janumet XR)
Temperature Control Standards
Ideal Storage Temperature: 20°C to 25°C (68°F to 77°F).
Allowable Temperature Fluctuation Range: 15°C to 30°C (59°F to 86°F).
Storage Environment Requirements: Store in a dry area with the container tightly sealed.
Key Points for Packaging Management
Maintenance of Original Packaging: The original packaging must be retained, and the bottle cap must be kept tightly closed.
Child Safety Protection: Store the product in an area that is out of the reach of children.
Usage and Handling Specifications: Reseal the container immediately after each dose is taken.
