Tabrecta(Capmatinib) Side Effects

A profile of common and serious adverse reactions requiring monitoring.

Side Effects

The most frequently reported adverse reactions associated with TABRECTA include peripheral edema, nausea, musculoskeletal pain, fatigue, vomiting, dyspnea, cough, and decreased appetite. These were observed in 20% or more of patients in clinical trials. The drug also carries warnings for more serious, though less common, adverse reactions such as interstitial lung disease/pneumonitis, hepatotoxicity evidenced by increased liver enzymes, and pancreatic toxicity indicated by elevated amylase and lipase. Laboratory abnormalities commonly include decreased albumin and increased creatinine.