Duvyzat (givinostat) is an oral suspension taken twice daily with food . The dosage is weight-based (e.g., 2.5–6 mL twice daily for different weight ranges) and administered using the provided graduated oral syringe.
Shake the bottle for at least 30 seconds before each use to ensure homogeneity . Prior to treatment, baseline platelet counts and triglycerides must be tested, and therapy should not start if platelets are <150 x 10⁹/L . Adjustments may be needed for side effects like thrombocytopenia, diarrhea, or QTc prolongation . Avoid missed doses; do not double up.
Discontinue unused medication after 60 days of opening . Patients with cardiac conditions or taking CYP3A4/OCT2 substrates should be monitored closely . Always follow your healthcare provider's instructions and report adverse reactions promptly.

