How should I use Nexviazyme(Avalglucosidase alfa)?

Instructions on how the drug is to be prepared and administered.

Dosage and Administration

The dosage is weight-based: 20 mg/kg every two weeks for patients ≥30 kg, and 40 mg/kg every two weeks for those <30 kg. The lyophilized powder must be reconstituted with Sterile Water for Injection and subsequently diluted in 5% Dextrose. The infusion is administered intravenously with an incremental escalation in rate, starting at 1 mg/kg/hr, to mitigate infusion-associated reactions. The total infusion duration typically ranges from 4 to 7 hours.