How should I use Syprine(Trientine)?

This section outlines the recommended dosing regimen and critical administration instructions.

Dosing Guidance

The starting total daily dosage is between 300 mg and 3,000 mg, administered orally in two divided doses. The initial dose is determined using a specific conversion table when switching from penicillamine. The dosage must be individualized based on clinical assessment and regular monitoring of copper levels. It is imperative to administer CUVRIOR on an empty stomach, at least one hour before or two hours after food, and separated from other drugs or mineral supplements by specific time intervals to avoid interactions that impair absorption. Tablets must be swallowed whole.