How should I use XALKORI(Crizotinib)?

Dosage varies by indication, patient age, and body surface area, with specific recommendations for hepatic or renal impairment.

How to Take XALKORI

The recommended dose for adults with NSCLC or IMT is 250 mg orally twice daily. For pediatric and young adult patients with ALCL or IMT, the dose is based on body surface area: 280 mg/m² twice daily. It can be taken with or without food. Capsules must be swallowed whole; pellets must be emptied from their shells and taken with water. Dosage adjustments are required for moderate to severe hepatic impairment or severe renal impairment, and when used with strong CYP3A inhibitors.