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Metyrapone(Metopirone)

Names
Metopiron,Metyrapone,METOPIRON,美替拉酮,甲吡酮
Indicatons
Adult and pediatric patients, particularly for diagnosing adrenal insufficiency.
Price:
Manufacturer:
Novartis
Dosage form:
CAPSULE
Validity period:
24 months

Reminder: The outer packaging is for reference only, please purchase and use under the guidance of a pharmacist. For read by medical and pharmaceutical professionals only.

Metopirone(Metyrapone) Instructions:Uses,Dosage, Side Effects

Metyrapone, marketed under the brand name Metopirone, is an adrenal steroid synthesis inhibitor used primarily for the diagnostic evaluation of adrenal insufficiency. It works by inhibiting the 11-beta-hydroxylation reaction in the adrenal cortex, leading to reduced production of cortisol and corticosterone. The drug also stimulates the production of adrenocorticotropic hormone (ACTH) by removing the inhibitory feedback of cortisol. 

In clinical practice, Metyrapone is used as part of diagnostic tests to assess adrenal function. It is especially valuable for evaluating patients with suspected adrenal insufficiency. It is administered orally in the form of soft gelatin capsules, typically in a dose of 30 mg/kg (maximum 3 grams), and it is evaluated through measuring 11-desoxycortisol and ACTH levels.

Generic name
Metyrapone(Metopirone)
English name
Metyrapone
Alternative Names
Metopiron,Metyrapone,METOPIRON,美替拉酮,甲吡酮
Drug prices
Indications

Metopirone is indicated for use in the diagnosis of adrenal insufficiency in both adult and pediatric patients when combined with other diagnostic tests. It is primarily used for assessing adrenal function, including testing for conditions like Cushing's syndrome and adrenal insufficiency.

Therapeutic Target
adrenal cortex
Active Ingredients
Metyrapone
Dosage Form
CAPSULE
Specifications
250mg*18capsules/bottle
Dosage and Administration

The recommended dose for the Single-Dose Short Test is 30 mg/kg of body weight, administered at midnight.

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