Who can use Fostamatinib(Tavalisse)?

Fostamatinib (brand name Tavalisse) is primarily indicated for adults with chronic immune thrombocytopenia (ITP), a condition characterized by low platelet counts due to immune system dysfunction. It is used when other treatments, such as corticosteroids, immunoglobulins, or splenectomy, have failed to maintain adequate platelet levels.

As an oral spleen tyrosine kinase (SYK) inhibitor, it reduces platelet destruction by modulating immune responses. Eligibility typically requires confirmed ITP diagnosis, persistent low platelets despite prior therapies, and no contraindications like severe hepatic impairment. Healthcare providers assess individual cases to ensure its benefits outweigh risks, such as potential infections or hypertension.